ProfDistS: (profile-) distance based phylogeny on sequence - structure alignments
نویسندگان
چکیده
MOTIVATION The Profile Neighbor Joining (PNJ) algorithm as implemented in the software ProfDist is computationally efficient in reconstructing very large trees. Besides the huge amount of sequence data the structure is important in RNA alignment analysis and phylogenetic reconstruction. RESULTS For this ProfDistS provides a phylogenetic workflow that uses individual RNA secondary structures in reconstructing phylogenies based on sequence-structure alignments-using PNJ with manual or iterative and automatic profile definition. Moreover, ProfDistS can deal also with protein sequences.
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عنوان ژورنال:
- Bioinformatics
دوره 24 20 شماره
صفحات -
تاریخ انتشار 2008